FUJIFILM Wako Chemicals U.S.A. Corp's Anti Phosphorylated Tau S262, Rat Monoclonal Antibody(TIP1-35) is a Rat monoclonal antibody. It reacts with Homo Sapiens, Human, and Non-Human Primate. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunocytochemistry, and Western Blot.
Description
Tau is one type of microtubule-binding protein that is primarily expressed within the neurons of the central nervous system and is involved in the modulation of microtubule stability. In Alzheimer's disease, the formation of neurofibrillary tangles with accumulated phosphorylated Tau proteins is known to occur. Since correlations between the occurrence frequency of neurofibrillary tangles and severity of dementia were reported, neurofibrillary tangles have been studied for determination of the causes and development of therapeutic agents for Alzheimer's disease. This product is a rat monoclonal antibody which recognizes Tau phosphorylated at the 262th serine